Thanks for the response. For some of the experiments we run, we collect data on event-locked physiological responses to stimuli (e.g., an increase in skin conductance when a particular image is presented). In our current in-lab set-up, the task computer sends a trigger to a nearby physio-data-collecting computer to tell it exactly when a stimulus is presented, so the event-related skin conductance response can be accurately measured. We’re trying to find software that can be used to run experiments online and in-lab, but, to run experiments in-lab, we’d need the software to be able to send signals to a nearby computer collecting physiological data, very rapidly, rather than just sending data to a distant URL. I was curious if there’s any way to do this through PennController, though it sounds like it might not be designed for that sort of thing.